Triboelectric nanogenerator ( TENG) technology has been rapidly developed in the field of self-generation and intelligent sensing due to non-contact inductive measurement method. However, because of the material characteristics and environmental factors on the electrification process and charge transfer process between friction interfaces, it is difficult to achieve accurate control and modulation. Therefore, a gas-liquid intermittent triboelectric nanogenerator ( L-S TENG) detection technology is proposed to realize real-time monitoring of the types and physical characteristics of flow medium in PTFE tube. By analyzing the influence of environmental factors and structural parameters of the system, the mechanism and influence law of liquid-gas-solid three-phase in the contact electrification and induced electrical output process are revealed. It is found that the open circuit voltage increases significantly with the increase of the copper electrode width. With the width from 1 mm to 3 mm, the voltage increases by 1. 32 times. When the width increases to 6 mm, it increases by 1. 9 times. When the liquid temperature increases from 1℃ to 55℃ , the open circuit voltage increases firstly and then decreases. As the tube ages, the number of electrons transferred to PTFE tube decreases, the number of charge induced by copper electrode decreases, and the power conversion efficiency decreases. With the increase of humidity, the internal friction electric effect between the phase interfaces weakens, and the open circuit voltage decreases. Under laser action, it can effectively stimulate the energy level of carriers on the interface, so that the output performance and power conversion efficiency of the system are greatly improved.