To improve the vibration environment of the micro-nano space camera during launch and avoid damage, a passive vibration isolation system is designed for the mission requirements of micro-nano space camera. Firstly, the camera vibration isolation system model is formulated and the response characteristics of the system is studied. Then, the vibration isolation system is decoupled and compared with the traditional method. Based on the camera parameters and the vibration isolation system, the passive rubber vibration isolator structure is calculated and designed. The fundamental frequency is 120 Hz and the mass fraction of camera is 1. 7 % . Finally, the dynamic simulation of the vibration isolation system is implemented by the finite element analysis method. The vibration tests of the space camera and the vibration isolation system are carried out. Experimental results show that the isolation efficiency of the passive vibration isolation system for the sinusoidal vibration and random vibration response of the micro-nano space camera can reach 55 % and 81 % , respectively. The validity and rationality of the vibration isolation system are verified.